D32Y (p.Asp32Tyr) variant of MCM6 (Q14566)
D32Y (p.Asp32Tyr) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
D32Y (p.Asp32Tyr) variant details
- p.Asp32Tyr
- gnomAD rs1341194126
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.29
- CADD 27.60
- PolyPhen-2 0.32
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available