D20N (p.Asp20Asn) variant of MCM6 (Q14566)
D20N (p.Asp20Asn) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
D20N (p.Asp20Asn) variant details
- p.Asp20Asn
- TOPMed rs1267930393
- gnomAD rs1267930393
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- REVEL 0.45
- CADD 28.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available