D109E (p.Asp109Glu) variant of MCM6 (Q14566)
D109E (p.Asp109Glu) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
D109E (p.Asp109Glu) variant details
- p.Asp109Glu
- ExAC rs760949511
- gnomAD rs760949511
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.13
- CADD 13.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available