C91R (p.Cys91Arg) variant of MCM6 (Q14566)
C91R (p.Cys91Arg) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
C91R (p.Cys91Arg) variant details
- p.Cys91Arg
- ExAC rs756125742
- TOPMed rs756125742
- gnomAD rs756125742
- Missense
- Variant Prioritization Score for Impact Estimate 0.522
- REVEL 0.45
- CADD 23.90
- PolyPhen-2 0.53
- SIFT 0.66
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available