A50T (p.Ala50Thr) variant of MCM6 (Q14566)
A50T (p.Ala50Thr) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
A50T (p.Ala50Thr) variant details
- p.Ala50Thr
- TOPMed rs1455587430
- gnomAD rs1455587430
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.29
- CADD 24.20
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available