A107T (p.Ala107Thr) variant of MCM6 (Q14566)
A107T (p.Ala107Thr) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A107T (p.Ala107Thr) variant details
- p.Ala107Thr
- ExAC rs762691120
- TOPMed rs762691120
- gnomAD rs762691120
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.04
- CADD 20.60
- PolyPhen-2 0.02
- SIFT 0.57
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available