Y68F (p.Tyr68Phe) variant of MCM5 (P33992)
Y68F (p.Tyr68Phe) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
Y68F (p.Tyr68Phe) variant details
- p.Tyr68Phe
- gnomAD 22-35403242-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.13
- CADD 22.40
- PolyPhen-2 0.02
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available