Y63* (p.Tyr63Ter) variant of MCM5 (P33992)
Y63* (p.Tyr63Ter) in MCM5 (P33992) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
Y63* (p.Tyr63Ter) variant details
- p.Tyr63Ter
- gnomAD 22-35403227-AC-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.639
- CADD 27.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available