Y11C (p.Tyr11Cys) variant of MCM5 (P33992)
Y11C (p.Tyr11Cys) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
Y11C (p.Tyr11Cys) variant details
- p.Tyr11Cys
- gnomAD 22-35400470-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.26
- CADD 25.70
- PolyPhen-2 0.05
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available