Y11* (p.Tyr11Ter) variant of MCM5 (P33992)
Y11* (p.Tyr11Ter) in MCM5 (P33992) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
Y11* (p.Tyr11Ter) variant details
- p.Tyr11Ter
- ExAC rs766162364
- TOPMed rs766162364
- gnomAD rs766162364
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.671
- CADD 33.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available