T46T (p.Thr46Thr) variant of MCM5 (P33992)
T46T (p.Thr46Thr) in MCM5 (P33992) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
T46T (p.Thr46Thr) variant details
- p.Thr46Thr
- rs1191942718
- gnomAD 22-35400576-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.291
- CADD 15.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available