R33K (p.Arg33Lys) variant of MCM5 (P33992)
R33K (p.Arg33Lys) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R33K (p.Arg33Lys) variant details
- p.Arg33Lys
- gnomAD rs1381169659
- Missense
- Variant Prioritization Score for Impact Estimate 0.129
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.90
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available