Q25P (p.Gln25Pro) variant of MCM5 (P33992)
Q25P (p.Gln25Pro) in MCM5 (P33992) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
Q25P (p.Gln25Pro) variant details
- p.Gln25Pro
- gnomAD 22-35400507-GGGGC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.37
- CADD 32.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available