Q25E (p.Gln25Glu) variant of MCM5 (P33992)
Q25E (p.Gln25Glu) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
Q25E (p.Gln25Glu) variant details
- p.Gln25Glu
- gnomAD rs1296547517
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.13
- MetaLR 0.05
- MetaSVM -1.07
- CADD 17.20
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available