G16A (p.Gly16Ala) variant of MCM5 (P33992)
G16A (p.Gly16Ala) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
G16A (p.Gly16Ala) variant details
- p.Gly16Ala
- gnomAD rs1218665637
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.22
- MetaLR 0.06
- MetaSVM -1.11
- CADD 23.10
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available