F4S (p.Phe4Ser) variant of MCM5 (P33992)
F4S (p.Phe4Ser) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
F4S (p.Phe4Ser) variant details
- p.Phe4Ser
- gnomAD 22-35400449-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.584
- REVEL 0.51
- CADD 33.00
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available