F15S (p.Phe15Ser) variant of MCM5 (P33992)
F15S (p.Phe15Ser) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
F15S (p.Phe15Ser) variant details
- p.Phe15Ser
- gnomAD 22-35400482-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.43
- CADD 28.90
- PolyPhen-2 0.86
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available