D22N (p.Asp22Asn) variant of MCM5 (P33992)
D22N (p.Asp22Asn) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
D22N (p.Asp22Asn) variant details
- p.Asp22Asn
- ExAC rs778264069
- TOPMed rs778264069
- gnomAD rs778264069
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.13
- MetaLR 0.09
- MetaSVM -1.08
- CADD 24.10
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available