A26V (p.Ala26Val) variant of MCM5 (P33992)
A26V (p.Ala26Val) in MCM5 (P33992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A26V (p.Ala26Val) variant details
- p.Ala26Val
- TOPMed rs1932009617
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.05
- MetaLR 0.03
- MetaSVM -1.06
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-06)
- Structural context available