p.Ala15 Pro28del variant of MCM2 (P49736)
p.Ala15 Pro28del in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
p.Ala15 Pro28del variant details
- rs2074287456
- gnomAD 3-127599344-ATCCA
- Inframe Deletion
- Variant Prioritization Score for Impact Estimate 0.227
- CADD 20.60
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available