T9A (p.Thr9Ala) variant of MCM2 (P49736)
T9A (p.Thr9Ala) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
T9A (p.Thr9Ala) variant details
- p.Thr9Ala
- gnomAD 3-127599336-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.07
- MetaLR 0.00
- MetaSVM -0.91
- CADD 14.90
- PolyPhen-2 0.00
- SIFT 0.95
- Most common in the Non-Finnish European population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available