T39P (p.Thr39Pro) variant of MCM2 (P49736)
T39P (p.Thr39Pro) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T39P (p.Thr39Pro) variant details
- p.Thr39Pro
- Ensembl rs1576410104
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.23
- MetaLR 0.06
- MetaSVM -1.06
- CADD 23.30
- PolyPhen-2 0.18
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available