T35A (p.Thr35Ala) variant of MCM2 (P49736)
T35A (p.Thr35Ala) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
T35A (p.Thr35Ala) variant details
- p.Thr35Ala
- gnomAD 3-127599414-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0956
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.01
- CADD 9.72
- PolyPhen-2 0.00
- SIFT 0.81
- Population evidence available
- Structural context available
- Literature evidence available