S26F (p.Ser26Phe) variant of MCM2 (P49736)
S26F (p.Ser26Phe) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
S26F (p.Ser26Phe) variant details
- p.Ser26Phe
- gnomAD 3-127599388-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.19
- MetaLR 0.11
- MetaSVM -0.87
- CADD 27.40
- PolyPhen-2 0.48
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available