S12S (p.Ser12Ser) variant of MCM2 (P49736)
S12S (p.Ser12Ser) in MCM2 (P49736) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
S12S (p.Ser12Ser) variant details
- p.Ser12Ser
- gnomAD 3-127599347-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.204
- CADD 8.95
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available