R33R (p.Arg33Arg) variant of MCM2 (P49736)
R33R (p.Arg33Arg) in MCM2 (P49736) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
R33R (p.Arg33Arg) variant details
- p.Arg33Arg
- gnomAD 3-127599408-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.597
- CADD 10.50
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available