P42A (p.Pro42Ala) variant of MCM2 (P49736)
P42A (p.Pro42Ala) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P42A (p.Pro42Ala) variant details
- p.Pro42Ala
- gnomAD rs1174580506
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.22
- MetaLR 0.12
- MetaSVM -0.84
- CADD 23.60
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available