G61W (p.Gly61Trp) variant of MCM2 (P49736)
G61W (p.Gly61Trp) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
G61W (p.Gly61Trp) variant details
- p.Gly61Trp
- gnomAD 3-127599492-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.10
- MetaLR 0.08
- MetaSVM -1.09
- CADD 28.40
- PolyPhen-2 0.53
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available