G61R (p.Gly61Arg) variant of MCM2 (P49736)
G61R (p.Gly61Arg) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
G61R (p.Gly61Arg) variant details
- p.Gly61Arg
- gnomAD 3-127599492-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.09
- CADD 23.00
- PolyPhen-2 0.06
- SIFT 0.38
- Population evidence available
- Structural context available
- Literature evidence available