G29S (p.Gly29Ser) variant of MCM2 (P49736)
G29S (p.Gly29Ser) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
G29S (p.Gly29Ser) variant details
- p.Gly29Ser
- Ensembl rs2074288909
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.04
- MetaLR 0.05
- MetaSVM -1.07
- CADD 23.00
- PolyPhen-2 0.00
- SIFT 0.87
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available