G20D (p.Gly20Asp) variant of MCM2 (P49736)
G20D (p.Gly20Asp) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
G20D (p.Gly20Asp) variant details
- p.Gly20Asp
- gnomAD 3-127599370-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -1.07
- CADD 12.00
- PolyPhen-2 0.00
- SIFT 0.55
- Population evidence available
- Structural context available
- Literature evidence available