E67G (p.Glu67Gly) variant of MCM2 (P49736)
E67G (p.Glu67Gly) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
E67G (p.Glu67Gly) variant details
- p.Glu67Gly
- 1000Genomes rs201221422
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.15
- MetaLR 0.07
- MetaSVM -1.09
- CADD 25.40
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the 1KG:GBR population (allele frequency 0.0057)
- Structural context available