D36G (p.Asp36Gly) variant of MCM2 (P49736)
D36G (p.Asp36Gly) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
D36G (p.Asp36Gly) variant details
- p.Asp36Gly
- gnomAD 3-127599418-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.29
- MetaLR 0.07
- MetaSVM -1.08
- CADD 23.30
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available