D22N (p.Asp22Asn) variant of MCM2 (P49736)
D22N (p.Asp22Asn) in MCM2 (P49736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
D22N (p.Asp22Asn) variant details
- p.Asp22Asn
- gnomAD rs1321006847
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.06
- CADD 23.30
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available