S67F (p.Ser67Phe) variant of MCL1 (Q07820)
S67F (p.Ser67Phe) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S67F (p.Ser67Phe) variant details
- p.Ser67Phe
- cosmic curated COSV10588
- Ensembl rs1647975969
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.07
- CADD 17.80
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 3.8e-06)
- Structural context available