S67A (p.Ser67Ala) variant of MCL1 (Q07820)
S67A (p.Ser67Ala) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S67A (p.Ser67Ala) variant details
- p.Ser67Ala
- TOPMed rs1245371992
- gnomAD rs1245371992
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.01
- CADD 1.43
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available