S64I (p.Ser64Ile) variant of MCL1 (Q07820)
S64I (p.Ser64Ile) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S64I (p.Ser64Ile) variant details
- p.Ser64Ile
- ExAC rs770464201
- gnomAD rs770464201
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.11
- CADD 19.50
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the East Asian population (allele frequency 3e-05)
- Structural context available