S60C (p.Ser60Cys) variant of MCL1 (Q07820)
S60C (p.Ser60Cys) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S60C (p.Ser60Cys) variant details
- p.Ser60Cys
- Ensembl rs2101700214
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.09
- CADD 21.80
- PolyPhen-2 0.52
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.5e-07)
- Structural context available