S43W (p.Ser43Trp) variant of MCL1 (Q07820)
S43W (p.Ser43Trp) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S43W (p.Ser43Trp) variant details
- p.Ser43Trp
- cosmic curated COSV57189
- gnomAD rs1267652025
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.04
- CADD 21.90
- PolyPhen-2 0.19
- SIFT 0.02
- Most common in the East Asian population (allele frequency 0.00011)
- Structural context available