S25R (p.Ser25Arg) variant of MCL1 (Q07820)
S25R (p.Ser25Arg) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S25R (p.Ser25Arg) variant details
- p.Ser25Arg
- Ensembl rs1378207194
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.07
- CADD 18.60
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available