S25G (p.Ser25Gly) variant of MCL1 (Q07820)
S25G (p.Ser25Gly) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
S25G (p.Ser25Gly) variant details
- p.Ser25Gly
- TOPMed rs1647986714
- gnomAD rs1647986714
- Missense
- Variant Prioritization Score for Impact Estimate 0.0624
- REVEL 0.02
- CADD 7.15
- PolyPhen-2 0.00
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available