R45Q (p.Arg45Gln) variant of MCL1 (Q07820)
R45Q (p.Arg45Gln) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R45Q (p.Arg45Gln) variant details
- p.Arg45Gln
- Ensembl rs1004335558
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.07
- CADD 13.10
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the Latino/Admixed American population (allele frequency 3e-05)
- Structural context available