R34G (p.Arg34Gly) variant of MCL1 (Q07820)
R34G (p.Arg34Gly) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
R34G (p.Arg34Gly) variant details
- p.Arg34Gly
- ExAC rs748428410
- gnomAD rs748428410
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.05
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available