R30C (p.Arg30Cys) variant of MCL1 (Q07820)
R30C (p.Arg30Cys) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
R30C (p.Arg30Cys) variant details
- p.Arg30Cys
- ExAC rs771486484
- gnomAD rs771486484
- Missense
- Variant Prioritization Score for Impact Estimate 0.096
- REVEL 0.01
- CADD 16.00
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available