P66S (p.Pro66Ser) variant of MCL1 (Q07820)
P66S (p.Pro66Ser) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
P66S (p.Pro66Ser) variant details
- p.Pro66Ser
- TOPMed rs1647976538
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.04
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.5e-07)
- Structural context available