P65S (p.Pro65Ser) variant of MCL1 (Q07820)
P65S (p.Pro65Ser) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P65S (p.Pro65Ser) variant details
- p.Pro65Ser
- TOPMed rs1312196037
- gnomAD rs1312196037
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.09
- CADD 18.00
- PolyPhen-2 0.50
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available