P65R (p.Pro65Arg) variant of MCL1 (Q07820)
P65R (p.Pro65Arg) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P65R (p.Pro65Arg) variant details
- p.Pro65Arg
- TOPMed rs1473394310
- gnomAD rs1473394310
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.08
- CADD 23.20
- PolyPhen-2 0.60
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available