P31R (p.Pro31Arg) variant of MCL1 (Q07820)
P31R (p.Pro31Arg) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P31R (p.Pro31Arg) variant details
- p.Pro31Arg
- ExAC rs745465126
- TOPMed rs745465126
- gnomAD rs745465126
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.03
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the East Asian population (allele frequency 2.7e-05)
- Structural context available