P31L (p.Pro31Leu) variant of MCL1 (Q07820)
P31L (p.Pro31Leu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P31L (p.Pro31Leu) variant details
- p.Pro31Leu
- ExAC rs745465126
- TOPMed rs745465126
- gnomAD rs745465126
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.06
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 5.1e-05)
- Structural context available