N7K (p.Asn7Lys) variant of MCL1 (Q07820)
N7K (p.Asn7Lys) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
N7K (p.Asn7Lys) variant details
- p.Asn7Lys
- TOPMed rs1647991739
- gnomAD rs1647991739
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.14
- CADD 23.80
- PolyPhen-2 0.99
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available